CLINICAL TRIALS
Active clinical trials and verified researcher listings for ALS / Lou Gehrig's Disease, simplified into plain English.
ABOUT ALS / LOU GEHRIG'S DISEASE
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a rare terminal neurodegenerative disease defined by the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. ALS is the most common of the motor neuron diseases. ALS often presents with gradual muscle stiffness, twitches, weakness, and wasting. Motor neuron loss typically continues until the ability to eat, speak, move, and breathe without mechanical support is lost. At least 50% of people with ALS experience significant changes in thinking and behavior, with 15% of individuals going on to develop frontotemporal dementia. An ALS diagnosis is made based on a person's signs and symptoms, with additional testing conducted to rule out other potential causes. Depending on which areas of the body are affected first, ALS may be classified as limb-onset or bulbar-onset. Respiratory onset occurs in approximately 1–3% of cases.
Source: Wikipedia. For educational use only — not medical advice.
ACTIVELY RECRUITING TRIALS
COMMON QUESTIONS
Are there clinical trials currently recruiting for ALS / Lou Gehrig's Disease?
Yes. This page displays actively recruiting ALS / Lou Gehrig's Disease clinical trials sourced in real time from ClinicalTrials.gov. Use the filters to narrow by phase, status, and location.
How do I join a clinical trial for ALS / Lou Gehrig's Disease?
Browse the trials listed above, review the eligibility criteria for each study, and submit a contact request directly to the research team. You can also speak to your physician about a referral.
Are ALS / Lou Gehrig's Disease clinical trials free to participate in?
Most clinical trials cover the cost of the investigational treatment and all study-related visits. Some studies also offer compensation for time and travel. Always confirm costs and insurance coverage with the trial coordinator before enrolling.
What eligibility requirements apply to ALS / Lou Gehrig's Disease trials?
Requirements vary by study. Common criteria include a confirmed ALS / Lou Gehrig's Disease diagnosis, age range, prior treatments, and general health status. Each trial listing shows its specific inclusion and exclusion criteria.
What phases of ALS / Lou Gehrig's Disease trials are available?
ALS / Lou Gehrig's Disease trials span Phase I (safety testing), Phase II (effectiveness), Phase III (comparison to standard care), and Phase IV (post-approval monitoring). Phase II and III trials are most commonly open to new participants.